First successful uterine transplant with live birth happened in Sweden in 2014 and so far 72 cases of uterine transplantation were done globally, out of which 18 live births are reported. Over 6 Lakh women in India are born without a uterus and of late surrogacy has also been a subject in India hence, uterus transplant can serve as an alternative to surrogacy for people who want to give birth and experience their own pregnancy.
Uterus transplantation is a complex procedure and is surrounded by not only medical and psychological implications but also ethical, moral, and cultural concerns and expectations. Transplantation of a uterus, unlike any other organ transplantation, involves no less than four parties – recipient, donor, partner of the recipient, and the possible future child.
The aim of the procedure is to allow women with absolute uterine factor infertility to have a baby. Absolute Uterine factor infertility is caused due to congenital or surgical absence of the uterus or the presence of a non-functional uterus.
Uterus with its blood supply will be removed from the donor and transplanted to the recipient through the microvascular anastomosis. Before performing the transplant surgery; the recipient should undergo controlled ovarian hyperstimulation and egg collection before the transplant surgery.
Recipient husband’s sperm and recipients’ egg is fertilized by IVF-ICSI, Embryo cryopreservation will be performed in order to use them for embryo transfer after successful transplantation.
